CK-MB: Definition, Uses, and Clinical Overview
CK-MB is a laboratory measurement related to creatine kinase, an enzyme involved in cellular energy use. It is an “isoenzyme” (a specific form) that is found in higher concentrations in heart muscle compared with many other tissues. CK-MB is most commonly discussed in the evaluation of possible heart muscle injury, including heart attack (myocardial infarction). Today it is often used alongside, or in selected situations instead of, other cardiac blood tests such as troponin.